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Homoaconitate hydratase

WebFungi produce α-aminoadipate, a precursor for penicillin and lysine via the α-aminoadipate pathway. Despite the biotechnological importance of this pathway, the essential isomerization of homocitrate via homoaconitate to homoisocitrate has hardly been studied. Therefore, we analysed the role of homo … WebHomoaconitate hydratase Imported. Gene names. Name. aksA Imported. ORF names. J6P91_01040 Imported. Organism names. Organism. Methanobrevibacter sp Imported. Taxonomic identifier. 66852 NCBI. Taxonomic lineage. Archaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > …

851820 - Gene ResultLYS4 homoaconitate hydratase LYS4 []

Web19 nov. 2004 · Recent studies have implied that the isopropylmalate isomerase small subunit of the hyperthermophilic archaea Pyrococcus horikoshii (PhIPMI-s) functions as isopropylmalate isomerase in the leucine biosynthesis pathway, and as homoaconitase (HACN) in the lysine biosynthesis pathway via alpha-aminoadi … WebBRENDA - The Comprehensive Enzyme Information System. 4.2.1.36: homoaconitate hydratase. This is an abbreviated version! For detailed information about homoaconitate hydratase, go to the full flat file. middle schools in norfolk https://hickboss.com

The fungal α-aminoadipate pathway for lysine biosynthesis

Webhomoaconitate hydratase; homoaconitase; cis-homoaconitase; HACN; Lys4; LysF; 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase (incorrect) Class Lyases; Carbon-oxygen lyases; Hydro-lyases BRITE hierarchy Sysname (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [ (Z)-but-1-ene-1,2,4-tricarboxylate-forming] Reaction (IUBMB) WebHomoaconitate hydratase (homoaconitase) is an enzyme from the alpha-aminoadipate pathway of lysine biosynthesis, and has been identified in higher fungi and several … WebENZYME entry: EC. 4.2.1.36. The enzyme from the hyperthermophilic eubacterium Thermus thermophilus can catalyze the reaction shown above but cannot catalyze the previously described reaction, i.e. formation of homocitrate by hydration of cis-homoaconitate. The enzyme responsible for the conversion of cis-homoaconitate into … newspaper pressman duties

Homoaconitate hydratase — Wikipédia

Category:Aconitate Hydratase - an overview ScienceDirect Topics

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Homoaconitate hydratase

Information on EC 4.2.1.36 - homoaconitate hydratase

WebThe enzyme responsible for the conversion of cis-homoaconitate into homocitrate in T. thermophilus is unknown at present but the reaction can be catalysed in vitro using aconitate hydratase from pig (EC 4.2.1.3) [2]. Webhomoaconitate hydratase; homoaconitase; cis-homoaconitase; HACN; Lys4; LysF; 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase (incorrect) Class Lyases; Carbon-oxygen lyases; Hydro-lyases BRITE hierarchy Sysname (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [ (Z)-but-1-ene-1,2,4-tricarboxylate-forming] Reaction (IUBMB)

Homoaconitate hydratase

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Web24 okt. 2008 · Along with the homologous 2-methyl-cis-aconitate hydratase and dimethylmalate dehydratase proteins, those HACN proteins catalyze only half of an aconitase-like reaction (16, 17). The HACN enzymes catalyze the hydration of cis-homoaconitate to form homoisocitrate (18). Web4.2.1.36 homoaconitate hydratase IUBMB Comments Requires a [4Fe-4S] cluster for activity. The enzyme from the hyperthermophilic eubacterium Thermus thermophilus can …

WebHomoaconitase enzymes catalyze hydrolyase reactions in the α-aminoadipate pathway for lysine biosynthesis or the 2-oxosuberate pathway for methanogenic coenzyme B biosynthesis. Despite the homology of … WebFungi have evolved a unique α-amino-adipate pathway for lysine biosynthesis. The fungal-specific enzyme homoaconitate hydratase from this pathway is moderately similar …

WebAconitase (aconitate hydratase; EC 4.2.1.3), which catalyzes isomerization of citrate to isocitrate via cis -aconitate in the TCA cycle, is an enzyme highly sensitive to irreversible … WebCatalyzes the isomerization of citrate to isocitrate via cis-aconitate, a step in the citric acid cycle. Can also provide minor contributions to the reversible dehydration of (R) …

Web25 okt. 2024 · This subfamily is a subset of the larger HacA family (Homoaconitate hydratase family, TIGR01343) and is most closely related to the 3-isopropylmalate dehydratase, large subunits which form TIGR00170. This subfamily includes the members of TIGR01343 which are gene clustered with other genes of leucine biosynthesis.

Web29 mei 2006 · HACN (homoaconitase) is a member of a family of [4Fe-4S] cluster-dependent enzymes that catalyse hydration/dehydration reactions. The best characterized example of this family is the ubiquitous ACN (aconitase), which catalyses the dehydration of citrate to cis-aconitate, and the subsequent hydration of cis-aconitate to isocitrate. newspaper pots for seed startingWebPlants as well as pro- and eukaryotic microorganisms are able to synthesise lysine via de novo synthesis. While plants and bacteria, with some exceptions, rely on variations of the … newspaper price in 1959WebBN7_2032 homoaconitate hydratase [] Gene ID: 23464638, updated on 5-Aug-2024. Summary. Gene provides a unified query environment for genes defined by sequence … middle schools in orlando floridaWebPredicted to enable homoaconitate hydratase activity. Involved in lysine biosynthetic process via aminoadipic acid. Located in mitochondrion. [provided by Alliance of … newspaper priceWebAlthough we confirmed an essential contribution of homoaconitases from Saccharomyces cerevisiae and Aspergillus fumigatus, these enzymes only catalysed the interconversion … newspaper powerpoint designWebAconitases are iron-sulfur proteins which catalyze the reversible isomerization of citrate and isocitrate via cis -aconitate. While in mitochondria aconitase is part of the … middle schools in north little rockWeb10 apr. 2024 · HIGHLIGHTS who: Hao Fan and colleagues from the Sanya Institute Nanjing Agricultural University, Key Laboratory Agricultural Environmental Microbiology Nanjing, China have published the research: The AMP-Activated Protein Kinase (AMPK) Positively … The amp-activated protein kinase (ampk) positively regulates lysine biosynthesis induced … middle schools in north port