Human autoantigen database
WebAAgAtlas 1.0 provides a user-friendly interface to conveniently browse, retrieve, and download human autoantigen genes, their functional annotation, related diseases, and … Web1 Jan 2024 · Human serum autoantigens are a great resource of generating non-invasive biomarkers with well-established detection methods in the clinics, including the ELISA …
Human autoantigen database
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Web19 Oct 2016 · The database provides a user-friendly interface to conveniently browse, retrieve and download human autoantigens as well as their associated diseases. The … Web12 Mar 2024 · Autoantibodies are antibodies against host self-proteins (autoantigens), which play significant roles in homeostasis maintenance and diseases with autoimmune …
Web28 Jan 2024 · This database reveals that intracellular nucleic acid binding proteins and signaling molecules are the most likely to behave as autoantigens. Indeed, the historical flagship Ro (SSA) and La (SSB) autoantigens are proteins in these classes.
WebAutoantibodies are antibodies that are produced by the B-cell immune system against an individual’s own antigens and play pivotal roles in the maintenance of healthy individuals’ … WebWe believe this database will be a valuable resource to track and understand human autoantigens as well as to investigate their functions in basic and translational …
WebAutoantibodies are humoral antibodies against self-proteins and play vital roles in maintaining the homeostasis. Autoantibodies can also target posttranslational modifications (PTMs) of proteins and the identification of new PTM autoantibodies is important to identify biomarkers for the early diagnosis of cancer and autoimmune diseases.
Web29 May 2024 · Among the overlapping proteins, 12 were listed as known autoantigens in the AagAtlas dataset: alpha-crystallin B chain, fibroblast growth factor receptor 1 (FGFR1), histone deacetylase 1 and 3, keratin type I cytoskeletal 15 and 19 (KRT15 and KRT19), mitogen-activated protein kinase 9, melanoma antigen recognized by T-cells 1, … how has technology affected health careWeb19 Oct 2016 · Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (Over 39 million (Over 39 million highest rated pink moscato wineWebFrom the ‘Home’ page, the users can see the introduction of AAgAtlas 1.0 database and search for the gene or disease of their interest. From the ‘Browse & Download’, the users … highest rated ping pong paddlesWeb9 Feb 2000 · The autoantigens were shown to cluster in two discrete cell surface 'membrane blebs'. The larger blebs (called apoptotic bodies) contained predominantly Ro, La, snRNPs, and nucleosomal DNA. The smaller structures were recognized by autoantibodies specific for endoplasmic reticulum components, as well as Ro and ribosomal components [ 12 ]. how has technology benefited ushttp://opig.stats.ox.ac.uk/webapps/covabdab/ highest rated pinstriping tapeWebOf these, 23 have previously been identified as autoantigens according to the human autoantigen database AagAtlas . Gene ontology (GO) annotation analysis of the identified proteins’ molecular functions categorized several of them as involved in either the binding or catalytic activity ( Figure 2 B,C). highest rated pin nailersWeb1 Jan 2024 · Autoantibodies are produced to target an individual's own antigens (e.g. proteins). They can trigger autoimmune responses and inflammation, and thus, cause many types of diseases. Many high-throughput autoantibody profiling projects have been reported for unbiased identification of serological autoantigen-based biomarkers. how has technology affected travel