WebWhen evaluating the entire study period, the highest prevalence of use in pediatric patients was observed in Group J, albeit with a decreasing trend (with the proportion of patients with at least one prescription in a year ranging from 63.0% in 2008 to 48.2% in 2024), followed by Group A, showing an increasing trend (range from 12.9% in 2008 to 23.4% in 2024, with … WebThe plasma clearance of montelukast averages 45 mL/min in healthy adults. Following an oral dose of radiolabeled montelukast, 86% of the radioactivity was recovered in 5-day fecal collections and <0.2% was recovered in urine. Coupled with estimates of montelukast oral bioavailability, this indicates that
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WebGeneric Name Montelukast DrugBank Accession Number DB00471 Background. Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. 3 The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs. 3,4,5,6,7,8,9 Although capable of demonstrating effectiveness, the … Web17 Aug 2024 · Montelukast may be used for the treatment of asthma or allergic rhinitis. It inhibits bronchoconstriction, which is the narrowing of the airways resulting in breathing … Montelukast sodium is an oral leukotriene receptor antagonist. It is indicated for patients 6 months and older: 1. for the treatment of asthma as add-on therapy in … See more It has been known for some time that neuropsychiatric reactions may occur in association with montelukast treatment, and these reactions are listed as possible … See more A range of neuropsychiatric reactions has been reported in association with montelukast. Among these are: sleep disturbances, depression and agitation (may … See more Healthcare professionals and patients should continue to report any suspected adverse drug reactions associated with montelukast to the Yellow Card Scheme. It is … See more European Medicines Agency. Scientific Conclusions report. July 2024. Article citation: Drug Safety Update volume 13, issue 2: September 2024: 4. See more insert checkbox in outlook email