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WebMKPs may be particularly useful to unravel the function of MAPK cascades in plants. Recently, two MKPs, IBR5 and PHS1 have been shown to regulate MPK12 and MPK18 during auxin signalling and cortical microtubule stabiliza-tion (Lee et al., 2009; Walia et al., 2009). A third enzyme, MKP1, plays a role in genotoxic responses and resistance to Web21 mrt. 2024 · Monitor Publishing, Inc. 1701 Woodfield Rd Suite 920 Schaumburg, IL 60173 e-mail: [email protected] tel.: (773) 205-0303 fax (708) 667-0384 Web28 aug. 2012 · MKPs represent a distinct subfamily within a larger group of dual-specificity protein phosphatases. ... ERK2 has a K d of ~ 30 n m, but also associates with ERK2 in the dephosphorylated form, albeit with reduced affinity (the K d for DUSP6/MKP3 binding to dephosphorylated ERK2 is ~ 190 n m) [35,58,59]. oxygo troubleshooting guide