WebApr 14, 2024 · A 72-year-old man with history of smoking, cholangiocarcinoma, and urothelial carcinoma underwent a left upper lung lobectomy for invasive adenocarcinoma. ... Immunohistochemical studies revealed that the tumor cells stained positive for p40 (staining the basal cell layer, Figure 3), TTF-1 (staining the luminal cell layer, Figure 4) and … WebResults: GPC3 was detected in 20% of SCCs and 12% of UCs and PAX8 in 3% of SCCs, limited to the uterine cervix, and 10% of UCs. p40 Was found in 99% of SCCs and 96% of …
Upper Tract Urothelial Cancer - Johns Hopkins Medicine
WebAug 26, 2024 · p40 is a subtype of p63 protein expressed in squamous epithelial cells (including epidermis and hair follicles), urothelial cells, myoepithelial cells of the mammary gland, sweat gland and salivary gland and basal cells of the prostate, which are highly specific in labeling squamous epithelium [ 9 ]. WebApr 7, 2014 · However, in a metastatic setting, p40 as a strong surrogate antibody along with GATA3 can contribute to confirming a urothelial origin in cases in which the clinical differential diagnosis does not include entities with known GATA3 positivity. text field bootstrap 5
Immunohistochemical Evaluation of GATA3 Expression in Tumors …
WebUpper tract urothelial cancer (UTUC) is a subset of urothelial cancer that is found in the renal pelvis of the ureter. At Johns Hopkins, we have a team of specialist in the Greenberg Bladder Cancer Institute who work together to … WebFeb 4, 2024 · Urothelial carcinoma is the most common type of bladder cancer cancer in the United States; it accounts for up to 90% of all bladder cancers and up to 10% of all kidney cancers. Squamous cell carcinoma forms due to chronic infection or chronic inflammation in the bladder, such as when a foley catheter is left in place for an extended time. WebApr 14, 2024 · A 72-year-old man with history of smoking, cholangiocarcinoma, and urothelial carcinoma underwent a left upper lung lobectomy for invasive adenocarcinoma. ... Immunohistochemical studies revealed that the tumor cells stained positive for p40 (staining the basal cell layer, Figure 3), TTF-1 (staining the luminal cell layer, Figure 4) and … textfield background color mui