Protein functional domain search
WebbApolipoprotein (apo) E is a multifunctional protein with central roles in lipid metabolism, neurobiology, and neurodegenerative diseases. It has three major isoforms (apoE2, apoE3, and apoE4) with different effects on lipid and neuronal homeostasis. WebbMediator of DNA damage checkpoint protein 1 (MDC1) plays a vital role in DNA damage response (DDR) by coordinating the repair of double strand breaks (DSBs). Here, we …
Protein functional domain search
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Webb31 okt. 2024 · In order to delineate a better approach to functional studies, we have selected 23 missense mutations distributed in different domains of two lysosomal enzymes, to be studied by in silico analysis. In silico analysis of mutations relies on computational modeling to predict their effects. Various computational platforms are …
WebbcddApp is a Cytoscape extension that supports the annotation of protein networks with information about domains and specific functional sites from the National Center for Biotechnology Information's conserved domain database (CDD). WebbSequence ID. (Example) mja:MJ_1041. Local file name. Sequence data. Select motif libraries : ( Help ) Databases. Cut-off score. (Click each database to get help for cut-off …
WebbELM Candidates. The ELM candidates pages contain lists of candidate classes and instances awaiting curation, and can be extended by users: Anybody can submit … WebbMulticolor flow cytometric analysis of CD366 (TIM-3) expression on viable activated Mouse splenic leucocytes. BALB/c Mouse splenocytes were cultured for 4 days in the presence of plate-bound Purified NA/LE Hamster Anti-Mouse CD3e (Cat. No. 553057/567114; 10 μg/ml for coating), soluble Purified NA/LE Hamster Anti-Mouse CD28 (Cat. No. 567110/553294; …
WebbThe protein information resource (PIR) is an integrated bioinformatics resource supporting genomic and proteomic research efficiently. PIR is a member of the Universal Protein …
WebbProtein domains often correspond to structural domains which are self-stabilizing and fold independently of the rest of the protein chain. They may occur independently or as … red fridge under counterWebb26 maj 2024 · Proteins fold into 3-dimensional structures to carry out a wide variety of functions within the cell 1.Even though many functional regions of proteins are … red frill caladiumWebbGene-specific transcription factors (TFs) are key regulatory components of wireless courses, controlling, for example, cell growth, development, and strain responses. Their biological functions are determined by their molecular business, as exemplified by their structured DNA-binding domains tar … red frilly pantiesWebb二、蛋白质的 Domains查找,保守区域的查找有很多数据库可以进行查找分析,在这里我们了几个都可以进行分析的网站 1.Conserved Domains这个网站NCBI中的网站. … knot side tableWebb13 apr. 2024 · DNA methyltransferase 3A (DNMT3A) is a de novo cytosine methyltransferase responsible for establishing proper DNA methylation during mammalian development. Loss-of-function (LOF) mutations to DNMT3A, including the hotspot mutation R882H, frequently occur in developmental growth disorders and hematological … knot siteWebb27 juni 2024 · An ideal tool for displaying protein domains should 1) include a function to create a database containing all annotated transcripts that are merged with protein … knot sign inWebb12 feb. 2013 · The Conserved Domains Database (CDD) groups proteins that have strong sequence similarity to protein domain fingerprints and allows you to search these … red frilly knickers